Mediterranean to Caribbean – Rome, Barcelona & St. Maarten
•25 nights•MSC OperaCivitavecchia (Rome)🇮🇹La Romana🇩🇴
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About this cruise
A 25-night cruise from Civitavecchia (Rome) to La Romana, sailing on the evening of 29 October. It makes 14 port calls, starting with Genoa, Livorno (Florence/Pisa) and Marseille. The stops are in 12 countries, and calls last 8 to 17 hours. Typical highs for the time of year run from 16°C in Marseille to 29°C in Tortola (61 to 84°F). The cruise ends in La Romana on the morning of 23 November. MSC Opera (2004) carries up to 2,658 guests on 13 decks and has 4 restaurants, all of them included in the fare.
Prices
All cabins appear to be sold out. Check back later, availability may change.
Price History
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Oceanview
Balcony
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Check the flight prices
This cruise does not return to Civitavecchia (Rome). It ends in La Romana, so your flight home leaves from there.
Flying from
Arrive
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Ports Map
About the Ship
2,658Guests
13Decks
2004Year Built
275 metersLong
4 Dining Venues4 included · 0 extra
Itinerary
Civitavecchia (Rome), Italy
Day 1 – Civitavecchia (Rome) 🇮🇹Depart: 7:00 PM
Genoa, Italy
Day 2 – Genoa 🇮🇹Arrive: 8:00 AM | Depart: 6:00 PM
Livorno (Florence/Pisa), Italy
Day 3 – Livorno (Florence/Pisa) 🇮🇹Arrive: 8:00 AM | Depart: 6:00 PM
Marseille, France
Day 4 – Marseille 🇫🇷Arrive: 9:00 AM | Depart: 6:00 PM
Barcelona, Spain
Day 5 – Barcelona 🇪🇸Arrive: 7:00 AM | Depart: 4:00 PM
Day 6 – Sea day
Sea dayTangier, Morocco
Day 7 – Tangier 🇲🇦Arrive: 8:00 AM | Depart: 5:00 PM
Day 8 – Sea day
Sea dayDay 9 – Sea day
Sea dayDay 10 – Sea day
Sea dayDay 11 – Sea day
Sea dayDay 12 – Sea day
Sea dayDay 13 – Sea day
Sea dayDay 14 – Sea day
Sea daySt. John's, Antigua and Barbuda
Day 15 – St. John's 🇦🇬Arrive: 9:00 AM | Depart: 6:00 PM
Philipsburg, Netherlands
Day 16 – Philipsburg 🇳🇱Arrive: 9:00 AM | Depart: 6:00 PM
Basseterre, Saint Kitts and Nevis
Day 17 – Basseterre 🇰🇳Arrive: 8:00 AM | Depart: 6:00 PM
Day 18 – Sea day
Sea dayLa Romana, Dominican Republic
Day 19 – La Romana 🇩🇴Arrive: 7:00 AM | Depart: 11:30 PM
Catalina Island, Dominican Republic
Day 20 – Catalina Island 🇩🇴Arrive: 7:00 AM | Depart: 5:00 PM
Day 21 – Sea day
Sea dayBridgetown, Barbados
Day 22 – Bridgetown 🇧🇧Arrive: 9:00 AM | Depart: 7:00 PM
Fort-de-France, Martinique
Day 23 – Fort-de-France 🇲🇶Arrive: 8:00 AM | Depart: 7:00 PM
Pointe-à-Pitre, Guadeloupe
Day 24 – Pointe-à-Pitre 🇬🇵Arrive: 7:00 AM | Depart: 4:00 PM
Tortola, British Virgin Islands
Day 25 – Tortola 🇻🇬Arrive: 7:30 AM | Depart: 3:30 PM
La Romana, Dominican Republic
Day 26 – La Romana 🇩🇴Arrive: 9:00 AM
Adjacent sailings on MSC Opera
Previous sailingAlready sailed19-day gap · different port
Mediterranean Grand Tour – Riviera, Lisbon & Sardinia
Sep 30 – Oct 10, 2026 · 10 nights · 🇮🇹 Genoa
Next sailing
14 Night Cruise from La Romana
Nov 23 – Dec 7, 2026 · 14 nights · 🇩🇴 La Romana · no prices for 1 guest
Next bookable sailing
Sun-Kissed Island Adventure – Samana, St. Kitts & St. Maarten
Nov 23 – 30, 2026 · 7 nights · 🇩🇴 La Romana · from $4,174 pp